![]() (2014) “3D Live Fluorescence Imaging of Cellular Dynamics Using Bessel Beam Plane Illumination Microscopy”, Nature Protocols, 9, 1083-1011. (2016) “Imaging multicellular specimens with real-time optimized tiling light sheet selective plane illumination microscopy”, Nature Communications, 7:11088.ģ. (*Corresponding Author)Ģ. Fu, Q., Martin, B., Matus, D., Gao, L. * (2020) “A Versatile Tiling Light Sheet Microscope for Imaging of Cleared Tissues”, Cell Reports, 33:108349. It allows efficient ion introduction from atmospheric pressure environments to high vacuum environments with very limited pumping capacities.ġ. Chen, Y.L., Li, X.L., Zhang, D.D., Wang, C.H., Feng, R.L., Li, X.Z., Wen, Y., Xu, H., Zhang, Shirley X.Y., Yang, X., Chen, Y.Y., Feng, Y., Zhou, B., Chen, B.C., Lei, K., Cai S., * Jia, J.M., * Gao, L. ( )Ĭhemical & Engineering News / Science & Technology / Concentrates, “Interface boosts MS performance”, May 19, 2008, 86(20), 39-40.Ī news report about a discontinuous atmospheric pressure interface (DAPI, patented) I invented in the Purdue University during my Ph.D. The rover will be sent to the Mars in July 2020. ![]() Our invention, the discontinuous atmospheric pressure interface (DAPI), was used in the Mars Organic Molecule Analyzer (MOMA) of the latest ExoMars rover, “ROSALIND FRANKLIN”, to introduce ions from the Mars atmosphere to the mass analyzer vacuum chamber. It is the first light sheet microscopy technique that allows low invasive, high speed 3D fluorescence imaging of biological processes at submicron isotropic 3D spatial resolution.ĭPAI used in the ExoMars rover “ROSALIND FRANKLIN” Eric Betzig in the Janelia Research Campus of HHMI during my postdoctoral research. HHMI News, “New microscope produces dazzling 3D movies of live cells”, March 04, 2011.Įditor reviews and news reports on the Bessel beam plane illumination microscopy technique I worked on with Dr. Nature Biotechnology, “Bessel beams for light relief”, 2011, 29(4).īBC News, “Light sheets image life in 3D”. Nature, “Seeing cells with sheets of light”, 2011, 471, 268. Nature Methods, “Imaging life with thin sheets of light”, 2012, 9(1). It is the first light sheet microscopy technique that allows high speed, live 3D fluorescence imaging beyond the diffraction limit. Nature Methods, “Bessel beams beyond the limit”, 2013, 10Īn editor review on the Bessel beam structured illumination microscopy technique I developed with Dr. The technique is under commercialization by multiple companies. It is an effective light sheet microscopy technique enables low invasive 3D fluorescence imaging of multicellular specimens at high spatial and temporal resolution. Nature Methods, “Tunable light sheet microscopy”, 2016, 6Īn editor review about the tiling light sheet selective plane illumination microscopy (TLS-SPIM, patented) developed in my lab at the Stony Brook University.
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